Gene Expression Data
Assay Details
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Assay
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Reference:
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J:82351
Bondjers C, et al., Transcription profiling of platelet-derived growth factor-B-deficient mouse embryos identifies RGS5 as a novel marker for pericytes and vascular smooth muscle cells. Am J Pathol. 2003 Mar;162(3):721-9
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:3581541
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Gene symbol:
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Cspg4
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Gene name:
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chondroitin sulfate proteoglycan 4
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Antibody:
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anti-NG2 (AB5320)
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Detection system:
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Secondary antibody coupled to horseradish peroxidase
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Results
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Specimen
2C:
embryonic day 14.5
(more  )
Specimen
2C:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: blood vessel |
Present |
Regionally restricted |
2C
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In the brain, expression is present in the pericytes surrounding the capillaries.
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Specimen
2F:
embryonic day 14.5
(more )
Specimen
2F:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: arterial system |
Present |
Regionally restricted |
2F
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Expression is present in the vascular smooth muscle cells surrounding some of the larger arteries.
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| TS22: venous system |
Absent |
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2F
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There is no, or limited, expression in the veins.
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Specimen
2I:
embryonic day 14.5
(more )
Specimen
2I:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: renal cortex |
Present |
Regionally restricted |
2I
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Expression is present in the mesangial cells in the kidney.
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Specimen
2L:
embryonic day 14.5
(more )
Specimen
2L:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: lung mesenchyme |
Present |
Regionally restricted |
2L
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Expression is found scattered in the mesenchyme in areas corresponding to ongoing angiogenesis, around developing airways, and in vascular smooth muscle cells surrounding developing lung arterial branches.
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Specimen
2O:
embryonic day 14.5
(more )
Specimen
2O:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: gut |
Present |
Regionally restricted |
2O
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Expression is present in the mesenchymal cells immediately subjacent to the epithelium, where angiogensis is known to be active, as well as in the smooth muscle cell layers and in the smooth muscle cells of larger intestinal blood vessels.
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Specimen
3E:
embryonic day 14.5; Pdgfbtm1Cbet/Pdgfb +
(more )
Specimen
3E:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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Pdgfbtm1Cbet/Pdgfb+
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: brain |
Present |
Regionally restricted |
3E
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Expression is present in the pericytes located in the capillary walls of the brain.
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Specimen
3F:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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Pdgfbtm1Cbet/Pdgfbtm1Cbet
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: brain |
Present |
Regionally restricted |
3F
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Expression is present in the pericytes located in the capillary walls of the brain; there are fewer of these cells in the mutant compared to wild type.
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Analysis Tools