About   Help   FAQ
Tbx20tm1Akis
Targeted Allele Detail
Summary
Symbol: Tbx20tm1Akis
Name: T-box 20; targeted mutation 1, Andreas Kispert
MGI ID: MGI:3580099
Synonyms: Tbx20-
Gene: Tbx20  Location: Chr9:24632108-24685580 bp, - strand  Genetic Position: Chr9, 10.25 cM
Alliance: Tbx20tm1Akis page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:98806
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S1
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsLacZ cDNA followed by a floxed neo selection cassette was inserted into the start codon in the first exon. RFLP analysis and absence of transcript confirmed successful targeting of the locus. (J:98806)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 12 assay results
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tbx20 Mutation:  34 strains or lines available
References
Original:  J:98806 Singh MK, et al., Tbx20 is essential for cardiac chamber differentiation and repression of Tbx2. Development. 2005 Jun;132(12):2697-707
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/09/2024
MGI 6.23
The Jackson Laboratory