Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	H2-D1bm14
Name:	histocompatibility 2, D region locus 1; b haplotype mutation 14
MGI ID:	MGI:3577203
Synonyms:	H-2bo, H2bo, HZW42
Gene:	H2-D1  Location: Chr17:35482070-35486473 bp, + strand  Genetic Position: Chr17, 18.61 cM
Alliance:	H2-D1bm14 page

Strain of Origin:

C57BL/6By

Allele Type:    Spontaneous Mutation:    Nucleotide substitutions   Mutation details: This mutation on the H2b haplotype is the result of a glutamine to histidine change at amino acid residue 70. Mice display a reduced expression of the H-2.2 specificity. (J:97717, J:98122, J:106337)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any H2-D1 Mutation:	45 strains or lines available

Original:	J:98122 Morgan GM, et al., Studies of two H-2Db mutants: B6. C-H-2bm13 and B6.C-H-2bm14. Immunogenetics. 1980;11(4):341-9
All:	16 reference(s)