Phenotypes associated with this allele

• Allele Symbol: H2-D1^bm14
• Allele Name: b haplotype mutation 14
• Allele ID: MGI:3577203
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	H2-D1^bm14/H2-D1^bm14	C57BL/6	MGI:3577207

Genotype
MGI:3577207

hm1

• Allelic Composition: H2-D1^bm14/H2-D1^bm14
• Genetic Background: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

spinal cord inflammation ( J:97717 )

• inflammatory infiltrates seen in the spinal cord 45 days after intracranial infection with Theiler's Murine Encephalomyelitis virus

demyelination ( J:97717 )

• seen in the spinal cords of 50% of mice 45 days after intracranial infection with Theiler's Murine Encephalomyelitis virus

• 100% of mice showed demyelination 90 days after infection

immune system

abnormal T cell activation ( J:97717 )

• failed to generate a T cell response to VP2_121-130 viral peptide 2 fragment

spinal cord inflammation ( J:97717 )

• inflammatory infiltrates seen in the spinal cord 45 days after intracranial infection with Theiler's Murine Encephalomyelitis virus

hematopoietic system

abnormal T cell activation ( J:97717 )

• failed to generate a T cell response to VP2_121-130 viral peptide 2 fragment