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Gene Expression Data
Assay Details
Assay
Reference: J:89190 Poschl E, et al., Collagen IV is essential for basement membrane stability but dispensable for initiation of its assembly during early development. Development. 2004 Apr;131(7):1619-28
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:3576088
Gene symbol: Anxa5
Gene name: annexin A5
Reporter: lacZ
Direct Detection
Results
Specimen 7A +/+: embryonic day 10.5; Anxa5tm1Epo/Anxa5+ (more )
Structure Level Pattern Image Note
TS17: blood vessel Present 7A +/+
Specimen 7A -/-: embryonic day 10.5; Anxa5tm1Epo/Anxa5+, Del(8Col4a1-Col4a2)1Epo/Del(8Col4a1-Col4a2)1Epo (more )
Structure Level Pattern Image Note
TS17: blood vessel Present 7A -/-
Specimen 7B +/+ upper: embryonic day 10.5; Anxa5tm1Epo/Anxa5+ (more )
Structure Level Pattern Image Note
TS17: blood vessel Present 7B +/+ upper Expression is present in the perineural vascular plexus surrounding the neuroectoderm.
Specimen 7B -/- upper: embryonic day 10.5; Anxa5tm1Epo/Anxa5+, Del(8Col4a1-Col4a2)1Epo/Del(8Col4a1-Col4a2)1Epo (more )
Structure Level Pattern Image Note
TS17: blood vessel Present 7B -/- upper Expression is present in the perineural vascular plexus surrounding the neuroectoderm. In mutants the plexus is less dense than in wild type, and the capillaries are irregularly arranged and have irregular protrusions.
Specimen 7B +/+ lower: embryonic day 10.5; Anxa5tm1Epo/Anxa5+ (more )
Structure Level Pattern Image Note
TS17: blood vessel Present 7B +/+ lower Expression is present in the perineural vascular plexus surrounding the neuroectoderm.
Specimen 7B -/- lower: embryonic day 10.5; Anxa5tm1Epo/Anxa5+, Del(8Col4a1-Col4a2)1Epo/Del(8Col4a1-Col4a2)1Epo (more )
Structure Level Pattern Image Note
TS17: blood vessel Present 7B -/- lower Expression is present in the perineural vascular plexus surrounding the neuroectoderm. In mutants the plexus is less dense than in wild type, and the capillaries are irregularly arranged and have irregular protrusions.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory