Gene Expression Data
Assay Details
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Assay
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Reference:
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J:76363
Lonze BE, et al., Apoptosis, axonal growth defects, and degeneration of peripheral neurons in mice lacking CREB. Neuron. 2002 Apr 25;34(3):371-85
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:3574327
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Gene symbol:
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Nefm
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Gene name:
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neurofilament, medium polypeptide
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Results
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Specimen
2H:
embryonic day 17.5; Creb1tm2Gsc/Creb1 +
(more  )
Note: This section is through the L4/L5 DRG.
Specimen
2H:
(close  )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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Creb1tm2Gsc/Creb1+
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Age:
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embryonic day 17.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Note:
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This section is through the L4/L5 DRG.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS25: dorsal root ganglion |
Present |
Regionally restricted |
2H
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Expression is present in large diameter neurons.
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Specimen
2I:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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Creb1tm2Gsc/Creb1tm2Gsc
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Age:
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embryonic day 17.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Note:
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This section is through the L4/L5 DRG.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS25: dorsal root ganglion |
Present |
Regionally restricted |
2I
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Expression is present in large diameter neurons; there are fewer of them in the mutant compared to the wild type.
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Specimen
8A:
embryonic day 12.5
(more )
Note: It is possible that this is a CREB heterozygotic embryo.
Specimen
8A:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 12.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Note:
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It is possible that this is a CREB heterozygotic embryo.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: nervous system |
Present |
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8A
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Expression is present in neurons.
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Specimen
8B:
embryonic day 12.5
(more )
Note: This specimen is from the thoracic/abdominal level. It is possible that it is a CREB heterozygotic embryo.
Specimen
8B:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 12.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Note:
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This specimen is from the thoracic/abdominal level. It is possible that it is a CREB heterozygotic embryo.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: spinal nerve |
Present |
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8B
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Expression is present in neurons.
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Specimen
8C:
embryonic day 12.5
(more )
Note: This specimen is from the limb level. It is possible that it is a CREB heterozygotic embryo.
Specimen
8C:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 12.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Note:
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This specimen is from the limb level. It is possible that it is a CREB heterozygotic embryo.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: spinal nerve |
Present |
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8C
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Expression is present in neurons.
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Specimen
8D:
embryonic day 12.5
(more )
Note: It is possible that this is a CREB heterozygotic embryo.
Specimen
8D:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 12.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Note:
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It is possible that this is a CREB heterozygotic embryo.
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Specimen
8E:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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Creb1tm2Gsc/Creb1tm2Gsc
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Age:
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embryonic day 12.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: nervous system |
Present |
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8E
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Expression is present in neurons, but the nerve projections are different in mutants compared to wild type.
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Specimen
8F:
embryonic day 12.5; Creb1tm2Gsc/ Creb1tm2Gsc
(more )
Note: This specimen is from the thoracic/abdominal level.
Specimen
8F:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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Creb1tm2Gsc/Creb1tm2Gsc
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Age:
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embryonic day 12.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Note:
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This specimen is from the thoracic/abdominal level.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: spinal nerve |
Present |
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8F
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Expression is present in neurons, but the nerve projections are different in mutants compared to wild type.
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Specimen
8G:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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Creb1tm2Gsc/Creb1tm2Gsc
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Age:
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embryonic day 12.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Note:
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This specimen is from the limb level.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: spinal nerve |
Present |
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8G
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Expression is present in neurons, but the nerve projections are different in mutants compared to wild type.
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Specimen
8H:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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Creb1tm2Gsc/Creb1tm2Gsc
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Age:
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embryonic day 12.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: trigeminal nerve |
Present |
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8H
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Expression is present in neurons, but the nerve projections are different in mutants compared to wild type.
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Specimen
8I:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Baxtm1Sjk/Bax+
Creb1tm2Gsc/Creb1+
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Age:
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embryonic day 12.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: spinal nerve |
Present |
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8I
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Expression is present in neurons, but the nerve projections are different in mutants compared to wild type.
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Specimen
8J:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Baxtm1Sjk/Baxtm1Sjk
Creb1tm2Gsc/Creb1+
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Age:
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embryonic day 12.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: spinal nerve |
Present |
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8J
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Expression is present in neurons, but the nerve projections are different in mutants compared to wild type.
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Specimen
8K:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Baxtm1Sjk/Baxtm1Sjk
Creb1tm2Gsc/Creb1tm2Gsc
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Age:
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embryonic day 12.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: spinal nerve |
Present |
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8K
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Expression is present in neurons, but the nerve projections are different in mutants compared to wild type.
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