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Cd36obl
Chemically induced Allele Detail
Summary
Symbol: Cd36obl
Name: CD36 molecule; oblivious
MGI ID: MGI:3573941
Synonyms: Cd36m1Btlr, obl
Gene: Cd36  Location: Chr5:17986688-18093799 bp, - strand  Genetic Position: Chr5, 8.11 cM
Alliance: Cd36obl page
Mutation
origin
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsThis allele contains a T to A point mutation at position 1022 in exon 11, creating an early stop codon and removing 133 residues from the C-terminus of the polypeptide chain. Loss of these amino acids prevented formation of the second of two transmembrain domains. Western blot against antibodies for the amino terminal showed an absence of protein in whole cell extracts and supernatant. (J:96018)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cd36 Mutation:  32 strains or lines available
References
Original:  J:96018 Hoebe K, et al., CD36 is a sensor of diacylglycerides. Nature. 2005 Feb 3;433(7025):523-7
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory