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Gene Expression Data
Assay Details
Assay
Reference: J:95366 Kelly K, et al., Metalloprotease-disintegrin ADAM8: expression analysis and targeted deletion in mice. Dev Dyn. 2005 Jan;232(1):221-31
Assay type: RNA in situ
MGI Accession ID: MGI:3531641
Gene symbol: Adam8
Gene name: a disintegrin and metallopeptidase domain 8
Probe: Adam8 cDNA1
Probe preparation: Antisense labelled with P33 RNA
Visualized with: Autoradiography
Results
Specimen 1A,B: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: extraembryonic component Present Regionally restricted 1A/B Expression is in the giant trophoblast layer surrounding the embryo.
TS13: embryo Absent 1A/B

Specimen 1C: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: extraembryonic component Present Regionally restricted 1C Expression is in the giant trophoblast layer surrounding the embryo.
TS13: embryo Absent 1C

Specimen 1D,E: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS28: decidua Strong Regionally restricted 1D/E Expression is in the decidua basalis (mesometrial decidua).

Specimen 1F: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS28: decidua Strong Regionally restricted 1F Expression is in the decidua basalis (mesometrial decidua). Expressing cells were found between the diploid decidual cells around the uterine lumen, and around blood lacunae.

Specimen 1G,H: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: extraembryonic component Present Regionally restricted 1G/H Expression is in cells in the chorionic plate.
TS28: decidua Present Regionally restricted 1G/H Expression is in invading trophoblast cells.

Specimen 1I: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: allantois Absent 1I
TS13: embryo Absent 1I
TS28: decidua Present Regionally restricted 1I Expression is in invading trophoblast cells.

Specimen 2A,B: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: gonad Present 2A/B

Specimen 2C,D: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: neural tube mantle layer Weak 2C/D

Specimen Not Shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: gonad Absent
TS22: spinal cord Absent
TS22: femur cartilage condensation Present
TS22: fibula cartilage condensation Present
TS22: tibia cartilage condensation Present

Specimen 3A,B: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lower jaw mesenchyme Strong Regionally restricted 3A/B Expression is in cells surrounding the mandible.

Specimen 3C,D: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: chondrocranium Present Regionally restricted 3C/D Expression is in cells surrounding the basi-occipital bone.

Specimen 3E,F: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: axial skeleton thoracic region Present Regionally restricted 3F , 3E Expression is in cells surrounding the ribs.

Specimen 3G,H: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: primary palate mesenchyme Strong Spotted 3G/H

Specimen 3I,J: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: nose Strong Regionally restricted 3I/J Expression is in the epithelium next to cartilage primordia of the nasal sinuses.

Specimen 4A,B: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: thymus primordium Present Regionally restricted 4A/B

Specimen 4C,D: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: ductus venosus Present 4C/D
TS22: hepatico-cardiac vein Present 4C/D
TS22: inferior vena cava Present 4C/D
TS22: umbilical vein Present 4C/D
TS22: liver Present Single cells 4C/D Expression is in single cells scattered throughout the liver, and along tissue surrounding the major umbilical vessels.

Specimen 4E,F,G: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: gland Strong Regionally restricted 4E/F , 4G The authors state that expression is in a nest of cells in proximity to the thymus that may correspond to a developing lymph node.

Specimen 4H,I,J: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: venous system Present Regionally restricted 4H/I , 4J Expression is localized to one side of the vein (shown is thoracic vein).
TS22: arterial system Absent 4H/I , 4J

Specimen 4K,L,M: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: subclavian vein Present Regionally restricted 4M , 4K/L Expression is localized to one side of the vein (shown are subclavian and cardinal veins).
TS22: venous system Present Regionally restricted 4M , 4K/L Expression is localized to one side of the vein (shown are subclavian and cardinal veins).

Specimen 5A,B: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lymphatic system Present Regionally restricted 5A/B Expression is in cells located between the jugular vein and jugular lymph sac.

Specimen 5E,F: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: subclavian vein Present Regionally restricted 5E/F Asymmetric expression.


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory