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Slc9c1tm1Gar
Targeted Allele Detail
Summary
Symbol: Slc9c1tm1Gar
Name: solute carrier family 9, subfamily C (Na+-transporting carboxylic acid decarboxylase), member 1; targeted mutation 1, David L Garbers
MGI ID: MGI:3530647
Synonyms: NHE-
Gene: Slc9c1  Location: Chr16:45355672-45427364 bp, + strand  Genetic Position: Chr16, 29.53 cM
Alliance: Slc9c1tm1Gar page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:87248
Parent Cell Line:  SM1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsPart of exon 4 and exons 5-11 were replaced with a neo cassette. Northern blot confirmed the presence of a truncated transcript in mutant mice. Neither immunohistochemistry nor Western blot analysis showed the presence of a protein product of this allele. (J:87248)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Slc9c1 Mutation:  67 strains or lines available
References
Original:  J:87248 Wang D, et al., A new sperm-specific Na+/H+ exchanger required for sperm motility and fertility. Nat Cell Biol. 2003 Dec;5(12):1117-22
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory