Nherf2Gt(OST2298)Lex
Gene trapped Allele Detail
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| Symbol: |
Nherf2Gt(OST2298)Lex |
| Name: |
NHERF family PDZ scaffold protein 2; gene trap OST2298, Lexicon Genetics |
| MGI ID: |
MGI:3530645 |
| Synonyms: |
N2-, NHERF-2-, NHERF2-, Slc9a3r2Gt(IRESBetageo)524Lex |
| Gene: |
Nherf2 Location: Chr17:24858255-24869279 bp, - strand Genetic Position: Chr17, 12.43 cM, cytoband A3.3
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| Alliance: |
Nherf2Gt(OST2298)Lex page
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| Mutant Cell Line: |
OST2298 |
| Germline Transmission: |
Earliest citation of germline transmission:
J:128912
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| Parent Cell Line: |
Lex-1 (ES Cell)
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| Strain of Origin: |
129S5/SvEvBrd
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| Project Collection: |
Lexicon
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| Allele Type: |
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Gene trapped (Null/knockout, Reporter) |
| Mutation: |
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Insertion of gene trap vector
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Mutation details: The gene trap vector VICTR22 was inserted into intron 2. Western blot analysis revealed a complete absence of protein in various homozygous mutant tissues, including kidney, lung, stomach, heart, brain, and colon.
(J:128912)
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| Sequence Tags: |
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Sequence tag details (1 tag)
| Tag ID |
GenBank ID |
Method |
Tag Location (trapped strand)* |
Select |
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| Genome Context: |
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Genome Browser view of this mutation
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Nherf2 Mutation: |
23 strains or lines available
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| Original: |
J:128912 Broere N, et al., Cystic Fibrosis Transmembrane Conductance Regulator Activation Is Reduced in the Small Intestine of Na+/H+ Exchanger 3 Regulatory Factor 1 (NHERF-1)- but Not NHERF-2-deficient Mice. J Biol Chem. 2007 Dec 28;282(52):37575-84 |
| All: |
15 reference(s) |
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Analysis Tools
