Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Cebpatm1Dgt
Name:	CCAAT/enhancer binding protein alpha; targeted mutation 1, Daniel G Tenen
MGI ID:	MGI:3522010
Synonyms:	C/EBPalphaF
Gene:	Cebpa  Location: Chr7:34818718-34821353 bp, + strand  Genetic Position: Chr7, 21.02 cM
Alliance:	Cebpatm1Dgt page

Germline Transmission:	Earliest citation of germline transmission: J:94682
Parent Cell Line:	TC1/TC-1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: LoxP sites were inserted to flank the single exon and a neo cassette inserted downstream of the exon. Western blot of whole-cell lysates of adult liver and total bone marrow cells showed that protein was present in mutants. (J:94682)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

4 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Cebpa Mutation:	16 strains or lines available

Original:	J:94682 Zhang P, et al., Enhancement of hematopoietic stem cell repopulating capacity and self-renewal in the absence of the transcription factor C/EBP alpha. Immunity. 2004 Dec;21(6):853-63
All:	32 reference(s)