Tg(H2-Kb)1Rms
Transgene Detail
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| Symbol: |
Tg(H2-Kb)1Rms |
| Name: |
transgene insertion 1, Robyn M Slattery |
| MGI ID: |
MGI:3512454 |
| Synonyms: |
KbTg |
| Transgene: |
Tg(H2-Kb)1Rms Location: unknown
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| Alliance: |
Tg(H2-Kb)1Rms page
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(H2-Kb)1Rms expresses
1 gene
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Mutation details: A transgene expressing the murine H2-K b class I variant was derived from a 7.5-kb genomic clone. Dormant 150-bp loxP sites were inserted into the Hinc II site 5' of exon 1 and the Bam HI site in intron 3 of the construct. At the 3' end of the construct there is a 74-bp tail containing the 5' end of the HSV-1 thymidine kinase gene.
(J:87648)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Original: |
J:87648 Serreze DV, et al., MHC class II molecules play a role in the selection of autoreactive class I-restricted CD8 T cells that are essential contributors to type 1 diabetes development in nonobese diabetic mice. J Immunol. 2004 Jan 15;172(2):871-9 |
| All: |
1 reference(s) |
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Analysis Tools
