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Gene Expression Data
Assay Details
Assay
Reference: J:93603 Wine-Lee L, et al., Signaling through BMP type 1 receptors is required for development of interneuron cell types in the dorsal spinal cord. Development. 2004 Nov;131(21):5393-403
Assay type: Immunohistochemistry
MGI Accession ID: MGI:3511813
Gene symbol: Pax2
Gene name: paired box 2
Results
Specimen 6C: embryonic day 10.5 (more )
Note: Double labeled: red - Pax2; green - Lhx1 (assay MGI:3798812) and Lhx5 (assay MGI:3511810).
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted 6C Expression is in the DI4 interneurons.
Specimen 6D: embryonic day 10.5; Bmpr1atm1Bhr/Bmpr1atm2.1Bhr, Bmpr1btm1Kml/Bmpr1btm1Kml, Tg(Pou3f4-cre)32Cren/0 (more )
Note: Conditional mutant. Double labeled: red - Pax2; green - Lhx1 (assay MGI:3798812) and Lhx5 (assay MGI:3511810).
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted 6D Expression is in the DI4 interneurons. Their numbers are increased and they are dorsally expanded in the mutant.
Specimen 6G: embryonic day 10.5 (more )
Note: Double labeled: red - Pax2; green - Isl1 (assay MGI:3511818) and Isl2 (assay MGI:5318526).
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted 6G Expression is in the DI4 interneurons.
Specimen 6H: embryonic day 10.5; Bmpr1atm1Bhr/Bmpr1atm2.1Bhr, Bmpr1btm1Kml/Bmpr1btm1Kml, Tg(Pou3f4-cre)32Cren/0 (more )
Note: Conditional mutant. Double labeled: red - Pax2; green - Isl1 (assay MGI:3511818) and Isl2 (assay MGI:5318526).
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted 6H Expression is in the DI4 interneurons, but in the mutant this population is expanded and found adjacent to the roof plate.
Specimen 7E: embryonic day 11.5 (more )
Note: Double labeled: red - Pax2; green - Isl1 (assay MGI:3511818) and Isl2 (assay MGI:5318526).
Structure Level Pattern Image Note
TS19: neural tube lateral wall Present Regionally restricted 7E Expression is present in the DI4 and DI6 dorsal sensory interneurons and in the V0 and V1 ventral neuronal groups.
Specimen 7F: embryonic day 11.5; Bmpr1atm1Bhr/Bmpr1atm2.1Bhr, Bmpr1btm1Kml/Bmpr1btm1Kml, Tg(Pou3f4-cre)32Cren/0 (more )
Note: Conditional mutant. Double labeled: red - Pax2; green - Isl1 (assay MGI:3511818) and Isl2 (assay MGI:5318526).
Structure Level Pattern Image Note
TS19: neural tube lateral wall Present Regionally restricted 7F Expression in the DI6, V0 and V1 neuronal groups is unaffected in the mutant; expression in the DI4 neurons is shifted dorsally toward the roof plate but is otherwise unaffected.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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