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Gene Expression Data
Assay Details
Assay
Reference: J:93603 Wine-Lee L, et al., Signaling through BMP type 1 receptors is required for development of interneuron cell types in the dorsal spinal cord. Development. 2004 Nov;131(21):5393-403
Assay type: Immunohistochemistry
MGI Accession ID: MGI:3798812
Gene symbol: Lhx1
Gene name: LIM homeobox protein 1
Antibody: 4F2
Results
Specimen 6C: embryonic day 10.5 (more )
Note: Double labeled: green - Lhx1 and Lhx5; red - Pax2 (assay MGI:3511813).
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted 6C Expression is present in DI2, DI4, and DI6 interneurons.
Specimen 6D: embryonic day 10.5; Bmpr1atm1Bhr/Bmpr1atm2.1Bhr, Bmpr1btm1Kml/Bmpr1btm1Kml, Tg(Pou3f4-cre)32Cren/0 (more )
Note: Conditional mutant. Double labeled: green - Lhx1 and Lhx5; red - Pax2 (assay MGI:3511813).
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted 6D The number of DI2 interneurons are reduced fourfold in the mutant animals; they are found adjacent to the roof plate. The number of DI4 interneurons are increased and are dorsally expanded.
Specimen 7C: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: neural tube lateral wall Present Regionally restricted 7C Expression is present in three populations of dorsal sensory neurons--DI2, DI4 and DI6--and in two populations of ventral neurons--V0 and V1.
Specimen 7D: embryonic day 11.5; Bmpr1atm1Bhr/Bmpr1atm2.1Bhr, Bmpr1btm1Kml/Bmpr1btm1Kml, Tg(Pou3f4-cre)32Cren/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: neural tube lateral wall Present Regionally restricted 7D In the mutant expression is unaffected in the DI6 dorsal sensory neurons and V0 and V1 ventral neurons; the number of DI2 dorsal sensory is greatly reduced.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory