Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Chd7Flo
Name:	chromodomain helicase DNA binding protein 7; flouncer
MGI ID:	MGI:3511552
Synonyms:	WBE2
Gene:	Chd7  Location: Chr4:8690406-8867659 bp, + strand  Genetic Position: Chr4, 3.68 cM
Alliance:	Chd7Flo page

Strain of Origin:

C3HeB/FeJ

Allele Type:    Chemically induced (ENU) Mutation:    Nucleotide substitutions   Mutation details: A mutation in the splice donor site resulted in the S1864X substitution. This mutation putatively results in a protein lacking only the most C-terminal NLS, SANT, and BRK domains. (J:104123) Inheritance:    Semidominant

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

7 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Chd7 Mutation:	136 strains or lines available

Original:	J:93173 Pau H, et al., Characterization of a new mouse mutant, flouncer, with a balance defect and inner ear malformation. Otol Neurotol. 2004 Sep;25(5):707-13
All:	2 reference(s)