Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Sox15tm1Imad
Name:	SRY (sex determining region Y)-box 15; targeted mutation 1, Ibrahim M Adham
MGI ID:	MGI:3056078
Synonyms:	Sox15-
Gene:	Sox15  Location: Chr11:69546140-69547553 bp, + strand  Genetic Position: Chr11, Syntenic
Alliance:	Sox15tm1Imad page

Germline Transmission:	Earliest citation of germline transmission: J:93031
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neomycin resistance gene replaced a 2.5-kb fragment containing the 5' flanking region and part of exon 1, including sequence encoding the HMG domain. Northern and Western blot analyses confirmed inactivation of the gene. (J:93031)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sox15 Mutation:	14 strains or lines available

Original:	J:93031 Lee HJ, et al., Sox15 is required for skeletal muscle regeneration. Mol Cell Biol. 2004 Oct;24(19):8428-36
All:	2 reference(s)