All Phenotypes Sox15<tm1Imad> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Sox15^tm1Imad
targeted mutation 1, Ibrahim M Adham
MGI:3056078

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Sox15^tm1Imad/Sox15^tm1Imad	either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)	MGI:3056108

Allelic Composition	Sox15^tm1Imad/Sox15^tm1Imad
Genetic Background	either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sox15^tm1Imad mutation (0 available); any Sox15 mutation (14 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

muscle

abnormal myoblast differentiation ( J:93031 )

• cultured myoblasts show a marked delay in differentiation potential in vitro

increased satellite cell number ( J:93031 )

• skeletal muscle regeneration is attenuated after crush injury to the TA muscle

cellular

abnormal myoblast differentiation ( J:93031 )

• cultured myoblasts show a marked delay in differentiation potential in vitro

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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