Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Sobpjc-2J
Name:	sine oculis binding protein; Jackson circler 2 Jackson
MGI ID:	MGI:3055292
Gene:	Sobp  Location: Chr10:42878496-43050526 bp, - strand  Genetic Position: Chr10, 22.89 cM
Alliance:	Sobpjc-2J page

Strain of Origin:

B6.129S2-Il6tm1Kopf/J

Allele Type:    Spontaneous Mutation:    Single point mutation   Mutation details: This spontaneous mutation, discovered in a production colony at The Jackson Laboratory, was shown to be allelic with the original Jackson circler mutation by failure of the two alleles to complement one another. A G-to-T transversion occurs at coding nucleotide position 1894 (c.1894G>T) that converts the glycine codon at amino acid residue 632 to a stop codon (p.G632*). The resulting protein is reduced in length by 28%. (J:113021, J:137716) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Sobp Mutation:	40 strains or lines available

Original:	J:113021 Calderon A, et al., Cochlear developmental defect and background-dependent hearing thresholds in the Jackson circler (jc) mutant mouse. Hear Res. 2006 Nov;221(1-2):44-58
All:	2 reference(s)