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Rnu2-8nmf291
Chemically induced Allele Detail
Summary
Symbol: Rnu2-8nmf291
Name: U2 small nuclear RNA 8; neuroscience mutagenesis facility, 291
MGI ID: MGI:3054730
Gene: Rnu2-8  Location: unknown  Genetic Position: Chr11, Syntenic
Alliance: Rnu2-8nmf291 page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:87349
Parent Cell Line:  v6.4 (ES Cell)
Strain of Origin:  (C57BL/6J x 129S4/SvJae)F1
Mutation
description
Allele Type:    Chemically induced (other)
Mutation:    Intragenic deletion
 
Mutation detailsThis phenotypic allele was identified in an ethylmethanesulfonate (EMS) mutagenesis screen for neurological phenotypes. The molecular defect is a 5 base pair deletion between nucleotides 30 and 34 in a highly conserved region located in the U2 consensus branch site sequence (BSRS) and the linker region between the BSRS and the U2/U6 helix. (J:179357)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 3 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Rnu2-8 Mutation:  1 strain or line available
References
Original:  J:87349 JAX Neuroscience Mutagenesis Facility, Heritable mouse mutants from JAX NMF ENU Mutagenesis Program. MGI Direct Data Submission. 2004-7;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory