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Scn9atm1Jwo
Targeted Allele Detail
Summary
Symbol: Scn9atm1Jwo
Name: sodium channel, voltage-gated, type IX, alpha; targeted mutation 1, John N Wood
MGI ID: MGI:3053097
Synonyms: FNav1.7, Scn9atm1Jnw
Gene: Scn9a  Location: Chr2:66310424-66465306 bp, - strand  Genetic Position: Chr2, 39.13 cM
Alliance: Scn9atm1Jwo page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:92442
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsExons 14 and 15 remain floxed after the Flp mediated excision of an FRT-flanked neo in intron 15. Southern blot confirmed recombination. (J:92442)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Scn9a Mutation:  120 strains or lines available
References
Original:  J:92442 Nassar MA, et al., Nociceptor-specific gene deletion reveals a major role for Nav1.7 (PN1) in acute and inflammatory pain. Proc Natl Acad Sci U S A. 2004 Aug 24;101(34):12706-11
All:  14 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory