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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Scn9atm1Jwo
targeted mutation 1, John N Wood
MGI:3053097
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
Scn10atm2(cre)Jwo/Scn10a+
Scn9atm1Jwo/Scn9atm1Jwo
involves: 129 MGI:3053686


Genotype
MGI:3053686
cn1
Allelic
Composition
Scn10atm2(cre)Jwo/Scn10a+
Scn9atm1Jwo/Scn9atm1Jwo
Genetic
Background
involves: 129
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Scn10atm2(cre)Jwo mutation (3 available); any Scn10a mutation (102 available)
Scn9atm1Jwo mutation (0 available); any Scn9a mutation (120 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• inflammation does not result in thermal or mechanical hyperalgesia in mutants unlike in wild-type mice
• homozygotes are significantly less sensitive to noxious mechanical stimulation compared to wild-type mice
• mutants are about 20% less sensitive to noxious thermal stimulation compared to wild-type mice





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory