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Gene Expression Data
Assay Details
Assay
Reference: J:46929 Dunwoodie SL, et al., Msg1 and Mrg1, founding members of a gene family, show distinct patterns of gene expression during mouse embryogenesis. Mech Dev. 1998 Mar;72(1-2):27-40
Assay type: RNA in situ
MGI Accession ID: MGI:3046868
Gene symbol: Cited2
Gene name: Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
Probe: IMAGE clone 537128
Probe preparation: Antisense RNA
Assay notes: Expression analyses were performed either with this clone or clone W15571 (MGI:214487). The authors state that both riboprobes gave identical results.
Results
Specimen 6A,B: embryonic day 5.5 (more )
Structure Level Pattern Image Note
TS8: primitive endoderm Present Regionally restricted 6A , 6B Expression in visceral endoderm with higher expression in a ringe of proximal embryonic VE, greatest in a small coherent patch of VE cells.
Specimen 6C: embryonic day 7.0 (more )
Note: Primitive streak stage embryo.
Structure Level Pattern Image Note
TS10: embryo endoderm Present Graded 6C Expression is in anterior endoderm and is low in the posterior endoderm.
TS10: extraembryonic endoderm Weak 6C
TS10: embryo mesoderm Weak Regionally restricted 6C Expression is in nascent mesoderm.
TS10: embryo Weak Regionally restricted 6C Expression is in the head process.
Specimen 6D: embryonic day 7.0 (more )
Note: Primitive streak stage embryo.
Structure Level Pattern Image Note
TS11: embryo endoderm Present Regionally restricted 6D Expression is in anterioproximal endoderm.
TS11: embryo Weak Regionally restricted 6D Expression is in the head process.
TS11: embryo mesoderm Weak Regionally restricted 6D Expression is in nascent mesoderm.
Specimen 6E, left: embryonic day 7.0 (more )
Note: Late primitive streak stage embryo.
Structure Level Pattern Image Note
TS10: embryo endoderm Present Regionally restricted 6E left Expression is in anterioproximal endoderm.
TS10: embryo mesoderm Present Regionally restricted 6E left Expression is in posterior nascent mesoderm.
Specimen 6E, right: embryonic day 7.5 (more )
Note: Early neural plate stage embryo.
Structure Level Pattern Image Note
TS11: embryo endoderm Present Regionally restricted 6E right Expression is in anterioproximal endoderm.
TS11: embryo mesoderm Present Regionally restricted 6E right Expression is in posterior nascent mesoderm.
TS11: blood island Present 6E right
Specimen 6F: embryonic day 7.5 (more )
Note: Neural plate stage embryo.
Structure Level Pattern Image Note
TS11: embryo endoderm Present Regionally restricted 6F Expression is in the most anteroproximal endoderm.
TS11: embryo mesoderm Present Regionally restricted 6F Expression is in the rostral and posterior nascent mesoderm.
Specimen 7A,B: embryonic day 7.5 (more )
Note: Head-fold stage embryo.
Structure Level Pattern Image Note
TS11: embryo Present Regionally restricted 7A , 7B Expression is as a thin continuous line across the midline just rostral to the neural folds.
TS11: cardiogenic plate Present Spotted 7A , 7B
TS11: blood island Present 7A , 7B
TS11: embryo mesenchyme Present 7A , 7B
Specimen 7C: embryonic day 8.0 (more )
Note: 2-somite embryo.
Structure Level Pattern Image Note
TS12: trunk mesenchyme Present Regionally restricted 7C Expression is in the septum transversum.
Specimen 7D: embryonic day 8.0 (more )
Note: 5-somite embryo.
Structure Level Pattern Image Note
TS12: trunk mesenchyme Present Regionally restricted 7D Expression in two bands corresponding to the site where the future myocardium adjoins the splanchnic mesoderm, the site of the future septum transversum and at a more caudal site.
Specimen 7E,F: embryonic day 8.5 (more )
Note: 8-somite embryo.
Structure Level Pattern Image Note
TS12: trunk mesenchyme Present Regionally restricted 7F , 7E Expression in two bands corresponding to the site where the future myocardium adjoins the splanchnic mesoderm, the site of the future septum transversum and at a more caudal site.
TS12: future hindbrain Present 7E , 7F
TS12: future midbrain Present 7E , 7F
Specimen 7G,left: embryonic day 8.5 (more )
Note: 9-somite embryo.
Structure Level Pattern Image Note
TS13: head paraxial mesenchyme Present 7G left
TS13: septum transversum Present 7G left
TS13: trunk paraxial mesenchyme Present 7G left
TS13: future brain Present Regionally restricted 7G left Expression is in cranial neural crest.
TS13: somite 09 Strong Regionally restricted 7G left Expression is in the most recently formed somite.
TS13: trunk unsegmented mesenchyme Present 7G left
Specimen 7G, right: embryonic day 8.5 (more )
Note: 12-somite embryo.
Structure Level Pattern Image Note
TS14: head paraxial mesenchyme Present 7G right
TS14: septum transversum Present 7G right
TS14: trunk paraxial mesenchyme Present 7G right
TS14: future brain Present Regionally restricted 7G right Expression is in the cranial neural crest.
TS14: somite 12 Strong 7G right Expression is in the most recently formed somite.
TS14: trunk unsegmented mesenchyme Present 7G right
Specimen 7H: embryonic day 7.5 (more )
Note: Head-fold stage embryo. This is a transverse section of the embryo shown in (A).
Structure Level Pattern Image Note
TS11: heart Present Regionally restricted 7H Expression is in the cardiac mesoderm.
Specimen 7I: embryonic day 8.0 (more )
Note: 2-somite embryo.
Structure Level Pattern Image Note
TS12: trunk mesenchyme Present Regionally restricted 7I Expression is in the presumptive septum transversum.
TS12: blood island Present 7I
TS12: cardiac muscle tissue Present 7I
Specimen 7J: embryonic day 8.0 (more )
Note: 5-somite embryo. This is a midline sagittal section of the embryo shown in (D).
Structure Level Pattern Image Note
TS12: cardiac muscle tissue Present Regionally restricted 7J Expression is at the two extremities of the myocardium.
TS12: blood island Present 7J
Specimen 7K: embryonic day 8.5 (more )
Note: 8-somite embryo. This is a midline sagittal section of the embryo shown in (E).
Structure Level Pattern Image Note
TS12: cardiac muscle tissue Present Regionally restricted 7K Expression is at the two extremities of the myocardium, one site has stronger expression.
TS12: trunk mesenchyme Strong 7K Expression was strong in the septum transversum.
Specimen 7L: embryonic day 8.5 (more )
Note: 8-somite embryo.
Structure Level Pattern Image Note
TS12: future brain Present Regionally restricted 7L Expression is in neural crest which have infiltrated the cranial mesenchyme
Specimen 7M: embryonic day 8.5 (more )
Note: 8-somite embryo.
Structure Level Pattern Image Note
TS13: trunk somite Present Regionally restricted 7M Expression is in the dorsal somite.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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