Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Jak2tm1.1Kuw
Name:	Janus kinase 2; targeted mutation 1.1, Kay-Uwe Wagner
MGI ID:	MGI:3045147
Synonyms:	Jak2-
Gene:	Jak2  Location: Chr19:29229228-29290480 bp, + strand  Genetic Position: Chr19, 23.73 cM
Alliance:	Jak2tm1.1Kuw page

Germline Transmission:	Earliest citation of germline transmission: J:90883
Parent Cell Line:	RW-4 (ES Cell)
Strain of Origin:	129X1/SvJ

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: This allele is a derivative of Jak2tm1Kuw in which the loxP-flanked exon 2 was deleted in the germline by Cre-mediated recombination. (J:90883)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Jak2 Mutation:	57 strains or lines available

Original:	J:90883 Wagner KU, et al., Impaired alveologenesis and maintenance of secretory mammary epithelial cells in Jak2 conditional knockout mice. Mol Cell Biol. 2004 Jun;24(12):5510-20
All:	4 reference(s)