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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Jak2tm1.1Kuw
targeted mutation 1.1, Kay-Uwe Wagner
MGI:3045147
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Jak2tm1.1Kuw/Jak2tm1.1Kuw involves: 129X1/SvJ MGI:3045185


Genotype
MGI:3045185
hm1
Allelic
Composition		 Jak2tm1.1Kuw/Jak2tm1.1Kuw
Genetic
Background		 involves: 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Jak2tm1.1Kuw mutation (1 available); any Jak2 mutation (60 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
prenatal lethality, complete penetrance ( J:90883 )
• homozygous embryos die at midgestation

hematopoietic system
abnormal erythropoiesis ( J:90883 )
• defective definitive erythropoiesis




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory