Summary | Transgene origin | Transgene description | Phenotypes | Tumor data | Find Mice (IMSR) | References

Symbol:	Tg(MtTGFA)100Lmb
Name:	transgene insertion 100, Glenn Merlino
MGI ID:	MGI:3040889
Transgene:	Tg(MtTGFA)100Lmb  Location: unknown
Alliance:	Tg(MtTGFA)100Lmb page

Strain of Origin:

FVB/N

Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence) Mutation:    Insertion   Tg(MtTGFA)100Lmb expresses 1 gene Transgene expresses: Organism Expressed Gene Homolog in Mouse Note human TGFA (7039) Tgfa  (MGI:98724)   Mutation details: This transgene contains the inducible mouse metallothionein 1 promoter, cDNA of the wild-type allele of the human transforming growth factor alpha gene, and a human growth hormone polyadenylation signal. Line 100 carries ten copies of the transgene. (J:28452)

View phenotypes and curated references for all genotypes (concatenated display).

List all tumor models in MMHCdb carrying Tg(MtTGFA)100Lmb

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:28452 Jhappan C, et al., TGF alpha overexpression in transgenic mice induces liver neoplasia and abnormal development of the mammary gland and pancreas. Cell. 1990 Jun 15;61(6):1137-46
All:	9 reference(s)