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Per2tm1Jt
Targeted Allele Detail
Summary
Symbol: Per2tm1Jt
Name: period circadian clock 2; targeted mutation 1, Joseph S Takahashi
MGI ID: MGI:3040876
Synonyms: mPer2Luc, mPER2::LUC, mPer2Luciferase, mPer2::Lucki, Per2Luc
Gene: Per2  Location: Chr1:91343704-91387046 bp, - strand  Genetic Position: Chr1, 46.13 cM, cytoband C5
Alliance: Per2tm1Jt page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:89256
Parent Cell Line:  W4 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (No functional change, Reporter)
Mutation:    Insertion
 
Mutation detailsA luciferase gene and floxed neo cassette were inserted between exon 23 and the 3' UTR. Mutant transcript was detected in Northern blot of mutant brains and the Per2-Luc fusion protein was detected in Western blots of mutant kidneys. (J:89256)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Per2 Mutation:  71 strains or lines available
References
Original:  J:89256 Yoo SH, et al., PERIOD2::LUCIFERASE real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues. Proc Natl Acad Sci U S A. 2004 Apr 13;101(15):5339-46
All:  238 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory