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Gene Expression Data
Assay Details
Assay
Reference: J:73288 Sonnenberg-Riethmacher E, et al., Development and degeneration of dorsal root ganglia in the absence of the HMG-domain transcription factor Sox10. Mech Dev. 2001 Dec;109(2):253-65
Assay type: RNA in situ
MGI Accession ID: MGI:3039427
Gene symbol: Cdh6
Gene name: cadherin 6
Probe: Cadherin-6 probe2
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Assay notes: Specimens were fixed in 1% paraformaldehyde and embedded in 2% agaorose prior to vibratome sectioning.
Results
Specimen 4A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: dorsal root ganglion Present 4A
TS17: neural tube lateral wall Present Regionally restricted 4A Expression is in the ventral root.
Specimen 4B: embryonic day 10.5; Sox10tm1Weg/Sox10tm1Weg (more )
Structure Level Pattern Image Note
TS17: dorsal root ganglion Present 4B Expression in this mutant is the same as in wild-type embryos.
TS17: neural tube lateral wall Present Regionally restricted 4B Expression is in the ventral root.
Specimen 4C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: dorsal root ganglion Trace Regionally restricted 4C Residual expression is in the ventral-most part.
TS20: peripheral nervous system Present 4C
Specimen 4D: embryonic day 12.5; Sox10tm1Weg/Sox10tm1Weg (more )
Structure Level Pattern Image Note
TS20: dorsal root ganglion Present 4D
TS20: peripheral nervous system Present Regionally restricted 4D No expression along peripheral nerves, and only a few positive cells in close vicinity to the ganglia.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory