Tg(CD19-Tnfsf7)12Rvl
Transgene Detail
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| Symbol: |
Tg(CD19-Tnfsf7)12Rvl |
| Name: |
transgene insertion 12, Rene A W van Lier |
| MGI ID: |
MGI:3038715 |
| Synonyms: |
CD70TG (F12) |
| Transgene: |
Tg(CD19-Tnfsf7)12Rvl Location: unknown
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| Alliance: |
Tg(CD19-Tnfsf7)12Rvl page
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(CD19-Tnfsf7)12Rvl expresses
1 gene
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Mutation details: A genomic fragement including the 3 exons of the mouse Tnfsf7 gene was adjoined to the human CD19 promoter region. The CD19 promoter overexpressed Tnfsf7 in B cell specific manner. The copy number was determined to be 4.
(J:73129)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:73129 Arens R, et al., Constitutive CD27/CD70 Interaction Induces Expansion of Effector-Type T Cells and Results in IFNgamma-Mediated B Cell Depletion. Immunity. 2001 Nov;15(5):801-12 |
| All: |
2 reference(s) |
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Analysis Tools
