About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:58691 Hildebrand JD, et al., Shroom, a PDZ domain-containing actin-binding protein, is required for neural tube morphogenesis in mice. Cell. 1999 Nov 24;99(5):485-97
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:3037557
Gene symbol: Shroom3
Gene name: shroom family member 3
Reporter: lacZ
Direct Detection
Results
Specimen 2A: embryonic day 8.5-8.75; Shroom3Gt(ROSA53)Sor/Shroom3+ (more )
Structure Level Pattern Image Note
TS13: neural ectoderm Strong Regionally restricted 2A Expression was detected in the cranial neuroepithelium in the rostral portion of the embryo.
TS13: gut Present 2A
TS13: neural tube Present 2A
TS13: trunk paraxial mesenchyme Present 2A
TS13: head mesenchyme Absent 2A

Specimen 2B left: embryonic day 10.5; Shroom3Gt(ROSA53)Sor/Shroom3+ (more )
Structure Level Pattern Image Note
TS18: forebrain Present 2B left
TS18: gut Present 2B left
TS18: heart Present 2B left
TS18: neural tube Present 2B left
TS18: trunk somite Present 2B left
TS18: trunk Present Regionally restricted 2B left Expression was detected in the ventral body wall.

Specimen 2B right: embryonic day 10.5; Shroom3Gt(ROSA53)Sor/Shroom3+ (more )
Structure Level Pattern Image Note
TS18: forebrain Present 2B right
TS18: gut Present 2B right
TS18: heart Present 2B right
TS18: neural tube Present 2B right
TS18: trunk somite Present 2B right
TS18: trunk Present Regionally restricted 2B right Expression was detected in the ventral body wall.

Specimen 2C: embryonic day 12.5; Shroom3Gt(ROSA53)Sor/Shroom3+ (more )
Structure Level Pattern Image Note
TS20: embryo Present 2C

Specimen 2D: embryonic day 14.5; Shroom3Gt(ROSA53)Sor/Shroom3+ (more )
Structure Level Pattern Image Note
TS22: forebrain Present 2D
TS22: skeletal muscle Present 2D
TS22: hand Present Regionally restricted 2D Expression was detected in the distal tips of the digits.

Specimen 2E: embryonic day 8.5-8.75; Shroom3Gt(ROSA53)Sor/Shroom3+ (more )
Structure Level Pattern Image Note
TS13: neural ectoderm Strong Regionally restricted 2E Expression was detected in the cranial neuroepithelium in the rostral portion of the embryo.
TS13: gut Present Regionally restricted 2E Expression was detected in the foregut.
TS13: neural tube Present 2E
TS13: optic pit Present 2E
TS13: trunk paraxial mesenchyme Present 2E
TS13: head mesenchyme Absent 2E

Specimen 2F: embryonic day 8.5-8.75; Shroom3Gt(ROSA53)Sor/Shroom3+ (more )
Structure Level Pattern Image Note
TS13: neural tube Present 2F
TS13: trunk paraxial mesenchyme Present 2F
TS13: gut Present Regionally restricted 2F Expression was detected in the foregut.

Specimen 2G: embryonic day 8.5-8.75; Shroom3Gt(ROSA53)Sor/Shroom3+ (more )
Structure Level Pattern Image Note
TS13: neural tube Present 2G
TS13: trunk paraxial mesenchyme Present 2G
TS13: gut Present Regionally restricted 2G Expression was detected in the hindgut.

Specimen 2H: embryonic day 10.5; Shroom3Gt(ROSA53)Sor/Shroom3+ (more )
Structure Level Pattern Image Note
TS17: forebrain Present 2H
TS17: gut Present 2H
TS17: heart Present 2H
TS17: neural tube Present 2H
TS17: neural tube floor plate Present 2H
TS17: neural tube roof plate Present 2H
TS17: trunk somite Present 2H
TS17: trunk Present Regionally restricted 2H Expression was detected in the ventral body wall.

Specimen 2I: embryonic day 10.5; Shroom3Gt(ROSA53)Sor/Shroom3+ (more )
Structure Level Pattern Image Note
TS17: gut Present 2I
TS17: heart Present 2I
TS17: neural tube Present 2I
TS17: neural tube floor plate Present 2I
TS17: trunk somite Present 2I
TS17: trunk Present Regionally restricted 2I Expression was detected in the ventral body wall.

Specimen 2J: embryonic day 10.5; Shroom3Gt(ROSA53)Sor/Shroom3+ (more )
Structure Level Pattern Image Note
TS17: heart Present 2J
TS17: midgut Present 2J
TS17: neural tube Present 2J
TS17: neural tube floor plate Present 2J
TS17: neural tube roof plate Present 2J
TS17: trunk somite Present 2J
TS17: trunk Present Regionally restricted 2J Expression was detected in the ventral body wall.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/23/2024
MGI 6.23
The Jackson Laboratory