Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Lmo4tm2Thr
Name:	LIM domain only 4; targeted mutation 2, Terence H Rabbitts
MGI ID:	MGI:3035827
Synonyms:	Lmo4-GFP, Lmo4z
Gene:	Lmo4  Location: Chr3:143894291-143910981 bp, - strand  Genetic Position: Chr3, 68.61 cM
Alliance:	Lmo4tm2Thr page

Germline Transmission:	Earliest citation of germline transmission: J:88167
Parent Cell Line:	CCB (ES Cell)
Strain of Origin:	129S/SvEv-Gpi1c

Allele Type:    Targeted (Null/knockout, Reporter) Mutation:    Disruption caused by insertion of vector   Mutation details: A targeting vector was used to create an in-frame fusion of a 5' portion of exon 2 and a GFP-hygro cassette. The absence of endogenous transcript was indicated by Northern blot analysis of mutant embryos. (J:88167)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

7 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lmo4 Mutation:	9 strains or lines available

Original:	J:88167 Tse E, et al., Null mutation of the Lmo4 gene or a combined null mutation of the Lmo1/Lmo3 genes causes perinatal lethality, and Lmo4 controls neural tube development in mice. Mol Cell Biol. 2004 Mar;24(5):2063-73
All:	1 reference(s)