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Gene Expression Data
Assay Details
Assay
Reference: J:87163 Zhang Z, et al., Msx1/Bmp4 genetic pathway regulates mammalian alveolar bone formation via induction of Dlx5 and Cbfa1. Mech Dev. 2003 Dec;120(12):1469-79
Assay type: RNA in situ
MGI Accession ID: MGI:3028934
Gene symbol: Bmp4
Gene name: bone morphogenetic protein 4
Probe: Bmp4 cDNA5
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen Bmp4 E14.5: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lower jaw molar mesenchyme Present Uniform 2C Expression is in both the dental papilla and the dental follicle.
TS22: upper jaw molar mesenchyme Present Uniform 2C Expression is in both the dental papilla and the dental follicle.
TS22: lower jaw skeleton Present Regionally restricted 2C Expression is in the alveolar bone.
TS22: upper jaw skeleton Present Regionally restricted 2C Expression is in the alveolar bone.
Specimen Bmp4 E16.5: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: lower jaw molar mesenchyme Present Uniform 2D Expression is in both the dental papilla and the dental follicle.
TS24: upper jaw molar mesenchyme Present Uniform 2D Expression is in both the dental papilla and the dental follicle.
TS24: lower jaw skeleton Present Regionally restricted 2D Expression is in the alveolar bone.
TS24: upper jaw skeleton Present Regionally restricted 2D Expression is in the alveolar bone.
Specimen Bmp4 wt: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: head mesenchyme Present Regionally restricted 4C Expression is in the dental mesenchyme.
Specimen Bmp4 Cbfa-/-: embryonic day 12.5; Runx2tm1Mjo/Runx2tm1Mjo (more )
Structure Level Pattern Image Note
TS20: head mesenchyme Present Regionally restricted 4D Expression is in the dental mesenchyme. Expression in this mutant is the same as in wild-type embryos.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory