Summary | Mutation origin | Mutation description | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Urodtm1Kush
Name:	uroporphyrinogen decarboxylase; targeted mutation 1, James P Kushner
MGI ID:	MGI:2687172
Synonyms:	URO-D-
Gene:	Urod  Location: Chr4:116847162-116851610 bp, - strand  Genetic Position: Chr4, 53.41 cM
Alliance:	Urodtm1Kush page

Germline Transmission:	Earliest citation of germline transmission: J:66704
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A fragment encompassing exon 6 and portions of its flanking introns was replaced with a neomycin selection cassette inserted by homologous recombination. (J:66704)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Urod Mutation:	16 strains or lines available

Original:	J:66704 Phillips JD, et al., A mouse model of familial porphyria cutanea tarda. Proc Natl Acad Sci U S A. 2001 Jan 2;98(1):259-64
All:	3 reference(s)