Phenotypes associated with this allele
|
|
| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Urodtm1Kush mutation
(0 available);
any
Urod mutation
(16 available)
|
|
|
mortality/aging
|
|
• no fetuses observed between E7.5 and E9.5
|
Allelic
Composition |
Urodtm1Kush/Urod+
|
|
Genetic
Background |
involves: 129S1/Sv * 129X1/SvJ |
|
| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Urodtm1Kush mutation
(0 available);
any
Urod mutation
(16 available)
|
|
|
normal phenotype
|
|
• hepatic iron concentrations did not differ from those of wild-type mice through 1 year of age, though treatment with iron dextran elicited a significantly higher increase in hepatic iron in mutant mice than in wild-type mice
• urinary porphyrin concentrations did not differ from those of wild-type mice prior to treatment with delta-aminolevulinic acid (ALA), though treatment with either ALA alone or with both ALA and iron elicited significantly higher increases in porphyrin concentrations than in mutant mice than in wild-type mice
|
|
|
| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hfetm2Nca mutation
(1 available);
any
Hfe mutation
(34 available)
Urodtm1Kush mutation
(0 available);
any
Urod mutation
(16 available)
|
|
|
homeostasis/metabolism
liver/biliary system
Analysis Tools
