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Nanos3tm1Ysa
Targeted Allele Detail
Summary
Symbol: Nanos3tm1Ysa
Name: nanos C2HC-type zinc finger 3; targeted mutation 1, Yumiko Saga
MGI ID: MGI:2682607
Synonyms: nanos3-L
Gene: Nanos3  Location: Chr8:84900359-84911396 bp, - strand  Genetic Position: Chr8, 40.45 cM
Alliance: Nanos3tm1Ysa page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:86522
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsA lacZ cassette was inserted at the start codon of the first coding exon. A floxed neo cassette was inserted downstream of the coding region and was subsequently removed via cre mediated recombination. LacZ expression was detected in mutant mice. (J:86522)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 4 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nanos3 Mutation:  28 strains or lines available
References
Original:  J:86522 Tsuda M, et al., Conserved role of nanos proteins in germ cell development. Science. 2003 Aug 29;301(5637):1239-41
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory