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Gene Expression Data
Assay Details
Assay
Reference: J:79394 Ishibashi M, et al., A sonic hedgehog-dependent signaling relay regulates growth of diencephalic and mesencephalic primordia in the early mouse embryo. Development. 2002 Oct;129(20):4807-19
Assay type: RNA in situ
MGI Accession ID: MGI:2676621
Gene symbol: Fgfr3
Gene name: fibroblast growth factor receptor 3
Probe: Fgfr3 probe3
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 7L: embryonic day 9.0 (more )
Note: 13 somite stage.
Structure Level Pattern Image Note
TS13: future midbrain roof plate Present Regionally restricted 7L Expression detected in alar plates of caudal diencephalon and anterior midbrain, overlapping Tcf4 and Dbx1 domains.
TS13: future prosencephalon Present Regionally restricted 7L Expression detected in alar plates of caudal diencephalon and anterior midbrain, overlapping Tcf4 and Dbx1 domains.

Specimen 7M: embryonic day 9.0; Shhtm1Amc/Shhtm1Amc (more )
Note: 13 somite stage.
Structure Level Pattern Image Note
TS14: future diencephalon roof plate Weak Regionally restricted 7M Expression was downregulated.
TS14: future midbrain roof plate Weak Regionally restricted 7M Expression was downregulated.

Specimen 7N: embryonic day 9.0 (more )
Note: 20 somite stage.
Structure Level Pattern Image Note
TS15: diencephalon roof plate Strong Regionally restricted 7N Strong expression in alar plate of caudal diencephalon and anterior midbrain.
TS15: future midbrain roof plate Strong Regionally restricted 7N Strong expression in alar plate of caudal diencephalon and anterior midbrain.

Specimen 7O: embryonic day 9.0; Shhtm1Amc/Shhtm1Amc (more )
Note: 20 somite stage.
Structure Level Pattern Image Note
TS14: future diencephalon roof plate Absent 7O Expression downregulated to almost background levels.
TS14: future midbrain roof plate Absent 7O Expression downregulated to almost background levels.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory