Gene Expression Data
Assay Details
Assay
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Reference:
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J:83431
Morgan EA, et al., Loss of Bmp7 and Fgf8 signaling in Hoxa13-mutant mice causes hypospadia. Development. 2003 Jul;130(14):3095-109
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:2675827
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Gene symbol:
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Bmpr1b
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Gene name:
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bone morphogenetic protein receptor, type 1B
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Results
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Specimen
4C:
embryonic day 12.5
(more )
Specimen
4C:
(close )
Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Age:
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embryonic day 12.5
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Sex:
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Male
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Type:
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whole mount
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Structure |
Level |
Pattern |
Image |
Note |
TS20: genital tubercle |
Present |
Regionally restricted |
4C
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Expression was detected in the urethral plate epithelium and the genital shelf mesenchyme.
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TS20: anal region |
Present |
Regionally restricted |
4C
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Expression was detected in the rectum.
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Specimen
4D:
(close )
Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Hoxa13tm1.1Mrc/Hoxa13tm1.1Mrc
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Age:
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embryonic day 12.5
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Sex:
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Male
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Type:
|
whole mount
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Structure |
Level |
Pattern |
Image |
Note |
TS20: anal region |
Present |
Regionally restricted |
4D
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Expression was elevated in the rectal mesenchyme compared to wild type.
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Specimen
4I:
embryonic day 13.5
(more )
Specimen
4I:
(close )
Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
Age:
|
embryonic day 13.5
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Sex:
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Male
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Type:
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whole mount
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Specimen
4J:
(close )
Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Hoxa13tm1.1Mrc/Hoxa13tm1.1Mrc
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Age:
|
embryonic day 13.5
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Sex:
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Male
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Type:
|
whole mount
|
Structure |
Level |
Pattern |
Image |
Note |
TS21: genital tubercle of male |
Present |
Regionally restricted |
4J
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Expression was downregulated in mid-proximal urethral plate epithelium compared to wild type.
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