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Gene Expression Data
Assay Details
Assay
Reference: J:48424 Lebel M, et al., A deletion within the murine Werner syndrome helicase induces sensitivity to inhibitors of topoisomerase and loss of cellular proliferative capacity. Proc Natl Acad Sci U S A. 1998 Oct 27;95(22):13097-102
Assay type: Northern blot
MGI Accession ID: MGI:2675709
Gene symbol: Wrn
Gene name: Werner syndrome RecQ like helicase
Probe: Wrn cDNA4
Probe preparation: Double stranded DNA
Results
Image: 2C ©

 Sample Information Bands Other Sample Information
Lane AgeStructure 6.6 kb Size Not Specified (a) Amount Genetic BackgroundMutant Allele(s)Sex
+/+ P TS28: metanephros Present Not Applicable 5 µg; poly-A+ RNA either: (involves: 129S/SvEv) or (involves: 129S/SvEv * NIH Black Swiss) Not Specified
+/- P TS28: metanephros Present (b) Present (b) 5 µg; poly-A+ RNA either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * NIH Black Swiss) Wrntm1Led/Wrn+Not Specified
-/- P TS28: metanephros Absent Present 5 µg; poly-A+ RNA either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * NIH Black Swiss) Wrntm1Led/Wrntm1LedNot Specified
Notes:
(a) The transcript present in the mutant was of a lower molecular weight than that found in wild-types.
(b) Both bands are of equal intensity.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
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