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Gene Expression Data
Assay Details
Assay
Reference: J:84239 Waters ST, et al., Cloning and embryonic expression analysis of the mouse Gbx1 gene. Gene Expr Patterns. 2003 Jun;3(3):313-7
Assay type: RNA in situ
MGI Accession ID: MGI:2671701
Gene symbol: Gbx1
Gene name: gastrulation brain homeobox 1
Probe: Gbx1 cDNA2
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen Not Shown: embryonic day 6.5 (more )
Structure Level Pattern Image Note
TS9: embryo Absent
Specimen 2A: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: primitive streak Present 2A
Specimen 2C: embryonic day 8.25 (more )
Structure Level Pattern Image Note
TS12: lateral plate mesoderm Present 2C
TS12: future hindbrain Present Regionally restricted 2C Expression is in two lateral stripes.
TS12: allantois Present 2C
TS12: future spinal cord neural plate Present 2C
Specimen 2D: embryonic day 8.25 (more )
Structure Level Pattern Image Note
TS13: lateral plate mesoderm Present 2D
TS13: future hindbrain Present Regionally restricted 2D Expression is in two lateral stripes.
TS13: extraembryonic component Present Regionally restricted 2D Expression is in the allantois.
TS13: future spinal cord neural plate Present 2D
Specimen 2F: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: primitive streak Present 2F
TS11: embryo ectoderm Present Graded 2F The highest expression is posterior.
TS11: embryo mesoderm Present Graded 2F The highest expression is posterior.
Specimen 2G: embryonic day 8.5 (more )
Note: 5-10 somites.
Structure Level Pattern Image Note
TS12: future hindbrain Present Regionally restricted 2G Expression extends caudally from the prospective hindbrain, with stronger expression in rhombomeres 3 and 5.
Specimen 2H: embryonic day 8.5 (more )
Note: 5-10 somites.
Structure Level Pattern Image Note
TS12: future hindbrain Present Regionally restricted 2H Expression extends caudally from the prospective hindbrain, with stronger expression in rhombomeres 3 and 5.
Specimen 2I: embryonic day 8.5 (more )
Note: 5-10 somites. Double labeled: purple - Gbx1; red - Egr2 (Krox20; assay MGI:2672856).
Structure Level Pattern Image Note
TS12: future hindbrain Present Regionally restricted 2I Expression extends caudally from the prospective hindbrain, with stronger expression in rhombomeres 3 and 5.
Specimen 3A: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: optic vesicle Present Regionally restricted 3A Expression is distal.
Specimen 3C: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: migrating neural crest Present Regionally restricted 3C Expression is in neural crest cells migrating from r4 and r6/7.
Specimen 3D: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: optic vesicle Present Regionally restricted 3D Expression is distal.
Specimen 3E: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: pericardio-peritoneal canal Present Regionally restricted 3E Expression is limited to the right canal.
Specimen Not Shown: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: pericardio-peritoneal canal Present
Specimen 4A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: diencephalon Present Regionally restricted 4A Expression is ventral.
TS17: telencephalon Present Regionally restricted 4A Expression is in the medial ganglionic eminence (MGE).
TS17: branchial arch Absent 4A
TS17: limb Absent 4A
TS17: tail Absent 4A
Specimen 4C: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: neural tube Present Regionally restricted 4C Expression is in the ventricular zone.
Specimen 4E: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: gonad primordium mesenchyme Present 4E
Specimen 4F: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: diencephalon Present 4F
Specimen 4G: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: medial ganglionic eminence Present Regionally restricted 4G Exprression is in the medial ganglionic eminence mantle zone.
Specimen 4I: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: trunk dermomyotome Present Regionally restricted 4I Expression is in the dorsal edge.
Specimen 5A: embryonic day 10.5 (more )
Note: Also stained for Otx2 (assay MGI:2672857).
Structure Level Pattern Image Note
TS17: brain Present 5A
Specimen 5B: embryonic day 10.5; Gbx2tm1.1Mrt/Gbx2tm1.1Mrt (more )
Note: Also stained for Otx2 (assay MGI:2672857).
Structure Level Pattern Image Note
TS17: brain Present 5B
Specimen 5C wt: embryonic day 8.0 (more )
Structure Level Pattern Image Note
TS12: embryo Present 5C wt
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory