Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Ppp1r3ctm1Ars
Name:	protein phosphatase 1, regulatory subunit 3C; targeted mutation 1, Alan R Saltiel
MGI ID:	MGI:2662307
Synonyms:	PTG-
Gene:	Ppp1r3c  Location: Chr19:36709131-36714004 bp, - strand  Genetic Position: Chr19, 31.89 cM, cytoband C3
Alliance:	Ppp1r3ctm1Ars page

Germline Transmission:	Earliest citation of germline transmission: J:83297
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129/Sv

Allele Type:    Targeted (Null/knockout) Mutation:    Disruption caused by insertion of vector   Mutation details: The entire coding region was replaced with a neo cassette inserted by homologous recombination. Western blot analysis of adipose, liver, and muscle tissue showed reduced levels of protein in homozygous mutant mice. (J:83297)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	6 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ppp1r3c Mutation:	19 strains or lines available

Original:	J:83297 Crosson SM, et al., PTG gene deletion causes impaired glycogen synthesis and developmental insulin resistance. J Clin Invest. 2003 May;111(9):1423-32
All:	3 reference(s)