About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:45337 Manley NR, et al., Hox group 3 paralogous genes act synergistically in the formation of somitic and neural crest-derived structures. Dev Biol. 1997 Dec 15;192(2):274-88
Assay type: Immunohistochemistry
MGI Accession ID: MGI:2450071
Gene symbol: Nefm
Gene name: neurofilament, medium polypeptide
Antibody: anti-neurofilament clone 2H3
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 6A, +/+: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: trigeminal ganglion Present 6A
TS17: facial ganglion Present 6A
TS17: glossopharyngeal ganglion Present 6A
TS17: vagus ganglion Present 6A
Specimen 6B, aa: embryonic day 10.5; Hoxa3tm1Mrc/Hoxa3tm1Mrc (more )
Structure Level Pattern Image Note
TS17: trigeminal ganglion Present 6B
TS17: facial ganglion Present 6B
TS17: glossopharyngeal ganglion Present 6B There is a patch or positive cells in the correct location but with no apparent connection to the hindbrain in this particular mutant. 25% of the mutants had the proximal portion of this ganglion deleted.
TS17: vagus ganglion Present 6B
Specimen 6C, aa: embryonic day 10.5; Hoxa3tm1Mrc/Hoxa3tm1Mrc (more )
Structure Level Pattern Image Note
TS17: trigeminal ganglion Present 6C
TS17: facial ganglion Present 6C
TS17: glossopharyngeal ganglion Present 6C There is a fusion of the IXth and Xth ganglia in this mutant. This occured in 50% of the mutants.
TS17: vagus ganglion Present 6C There is a fusion of the IXth and Xth ganglia in this mutant. This occured in 50% of the mutants.
Specimen 6D, +/+: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: facial ganglion Present 6D
TS19: glossopharyngeal ganglion Present 6D
TS19: vagus ganglion Present 6D
Specimen 6E, aa: embryonic day 11.5; Hoxa3tm1Mrc/Hoxa3tm1Mrc (more )
Structure Level Pattern Image Note
TS19: facial ganglion Present 6E
TS19: glossopharyngeal ganglion Present 6E In this mutant this ganglion appears as a small patch.
TS19: vagus ganglion Present 6E
Specimen 6F, aa: embryonic day 11.5; Hoxa3tm1Mrc/Hoxa3tm1Mrc (more )
Structure Level Pattern Image Note
TS19: facial ganglion Present 6F
TS19: glossopharyngeal ganglion Present 6F A nearly complete fusion of the IXth and Xth ganglia, there is a small remnant of the IXth.
TS19: vagus ganglion Present 6F A nearly complete fusion of the IXth and Xth ganglia, there is a small remnant of the IXth.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/30/2025
MGI 6.24 		The Jackson Laboratory