Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Epha2Gt(ROSABetageo)CN3Yiw
Name:	Eph receptor A2; gene trap CN3, Yoichiro Iwakura
MGI ID:	MGI:2448472
Synonyms:	EphA2LacZ
Gene:	Epha2  Location: Chr4:141028551-141056695 bp, + strand  Genetic Position: Chr4, 73.67 cM, cytoband D-E
Alliance:	Epha2Gt(ROSABetageo)CN3Yiw page

Mutant Cell Line:	CN3
Germline Transmission:	Earliest citation of germline transmission: J:69393
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Gene trapped (Null/knockout, Reporter) Mutation:    Insertion of gene trap vector     Vector: ROSANBeta-geo     Vector Type: gene trap   Mutation details: A gene trap vector inserted into intron 1. Southern blot analysis indicated that the insertion occurred at a single site in the genome. Normal transcript was undetected by Northern blot analysis. An absence of full length protein was indicated by Western blot analysis. (J:69393)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	52 assay results
In Structures Affected by this Mutation:	6 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Epha2 Mutation:	96 strains or lines available

Original:	J:69393 Naruse-Nakajima C, et al., Involvement of EphA2 in the formation of the tail notochord via interaction with ephrinA1. Mech Dev. 2001 Apr;102(1-2):95-105
All:	8 reference(s)