Summary | Transgene origin | Transgene description | Expression | Recombinase activity | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(COL2A1-cre)1Wag
Name:	transgene insertion 1, Erwin F Wagner
MGI ID:	MGI:2445431
Synonyms:	Col2-Cre, collagen2a1-cre
Transgene:	Tg(COL2A1-cre)1Wag  Location: unknown
Alliance:	Tg(COL2A1-cre)1Wag page

Strain of Origin:

(C57BL/6 x CBA)F1

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(COL2A1-cre)1Wag expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Homolog in Mouse Note human COL2A1 (1280) Col2a1  (MGI:88452)   Mutation details: This transgene expresses cre recombinase under the control of human COL2A1 promoter and enhancer sequences. Human COL2A1 promoter and enhancer sequences drive transgene expression. Transgene expression is observed in chondrogenic tissues, the developing eye, epidermis, heart myocardium, and endoderm of the developing yolk sac. (J:60838)

Activity:	Tissue activity of this recombinase allele
Driver:	COL2A1 (human) Summary of all recombinase alleles driven by COL2A1. Comparative matrix view of recombinase activities Alliance human COL2A1 gene page

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

13 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:60838 Haigh JJ, et al., Conditional inactivation of VEGF-A in areas of collagen2a1 expression results in embryonic lethality in the heterozygous state. Development. 2000 Apr;127(7):1445-53
All:	4 reference(s)