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Tg(Hoxd11)1Ddu
Transgene Detail
Summary
Symbol: Tg(Hoxd11)1Ddu
Name: transgene insertion 1, Denis Duboule
MGI ID: MGI:2388473
Transgene: Tg(Hoxd11)1Ddu  Location: unknown  
Alliance: Tg(Hoxd11)1Ddu page
Transgene
origin
Strain of Origin:  (C57BL/6 x CBA)F2
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Hoxd11)1Ddu expresses 1 gene
 
Mutation detailsA 7 kb genomic fragment of mouse Hoxd11 lacking the negative regulatory element, region IX, was used as the transgene. (J:33614)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Notes
Two transgenic lines, a and b, were established which show similar transgene expression patterns. Founder a exhibits a higher level of transgene expression compared to founder b.
References
Original:  J:33614 Zakany J, et al., Functional equivalence and rescue among group 11 Hox gene products in vertebral patterning. Dev Biol. 1996 Jun 15;176(2):325-8
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory