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Wnt7btm1Parr
Targeted Allele Detail
Summary
Symbol: Wnt7btm1Parr
Name: wingless-type MMTV integration site family, member 7B; targeted mutation 1, Brian A Parr
MGI ID: MGI:2387443
Synonyms: Wnt7b-, Wnt7bD3, Wnt7bD3-4
Gene: Wnt7b  Location: Chr15:85419638-85466022 bp, - strand  Genetic Position: Chr15, 40.39 cM
Alliance: Wnt7btm1Parr page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:71583
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe gene was disrupted by replacement of part of exon 3 and part of intron 3 with a neomycin resistance cassette via homologous recombination. (J:71583)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 13 assay results
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Wnt7b Mutation:  17 strains or lines available
References
Original:  J:71583 Parr BA, et al., Wnt7b regulates placental development in mice. Dev Biol. 2001 Sep 15;237(2):324-32
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory