Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Dab2tm1Cpr
Name:	disabled 2, mitogen-responsive phosphoprotein; targeted mutation 1, Jonathan A Cooper
MGI ID:	MGI:2387166
Synonyms:	Dab2fl
Gene:	Dab2  Location: Chr15:6329269-6470193 bp, + strand  Genetic Position: Chr15, 2.15 cM, cytoband A2
Alliance:	Dab2tm1Cpr page

Germline Transmission:	Earliest citation of germline transmission: J:75911
Parent Cell Line:	AK7 (ES Cell)
Strain of Origin:	129S4/SvJaeSor

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: Exon 2, which encodes the phosphotyrosine binding (PTB) domain common to all known isoforms, was left flanked by single loxP sites after a floxed neo cassette was excised by in vitro cre mediated recombination. (J:75911)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Dab2 Mutation:	53 strains or lines available

Original:	J:75911 Morris SM, et al., Dual roles for the Dab2 adaptor protein in embryonic development and kidney transport. EMBO J. 2002 Apr 2;21(7):1555-64
All:	10 reference(s)