All Phenotypes Dab2<tm1Cpr> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Dab2^tm1Cpr
targeted mutation 1, Jonathan A Cooper
MGI:2387166

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Dab2^tm1Cpr/Dab2^tm1.1Cpr Meox2^tm1(cre)Sor/Meox2⁺	involves: 129S4/SvJaeSor * C57BL/6	MGI:3510687

Allelic Composition	Dab2^tm1Cpr/Dab2^tm1.1Cpr Meox2^tm1(cre)Sor/Meox2⁺
Genetic Background	involves: 129S4/SvJaeSor * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dab2^tm1.1Cpr mutation (0 available); any Dab2 mutation (54 available)
Dab2^tm1Cpr mutation (1 available); any Dab2 mutation (54 available)
Meox2^tm1(cre)Sor mutation (3 available); any Meox2 mutation (21 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

increased urine protein level ( J:75911 )

• Vitamin D binding protein and retinol binding protein found in the urine

renal/urinary system

increased urine protein level ( J:75911 )

• Vitamin D binding protein and retinol binding protein found in the urine

abnormal proximal convoluted tubule morphology ( J:75911 )

• reduced numbers of coated pits and endocytic vescicles near the apical membrane of the proximal tubules

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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