Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Kat2atm1Roth
Name:	K(lysine) acetyltransferase 2A; targeted mutation 1, Sharon Y Roth
MGI ID:	MGI:2386279
Synonyms:	Gcn5-, Gcn5delta, Gcn5l2-
Gene:	Kat2a  Location: Chr11:100595572-100603291 bp, - strand  Genetic Position: Chr11, 63.53 cM
Alliance:	Kat2atm1Roth page

Germline Transmission:	Earliest citation of germline transmission: J:65002
Parent Cell Line:	AB1 (ES Cell)
Strain of Origin:	129S7/SvEvBrd-Hprt1+

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion   Mutation details: The entire coding region of the endogenous gene was replaced with a cassette containing lacZ and neo. Transcript was undetected in homozygous mutant embryos via whole mount in situ hybridization. (J:65002)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	16 assay results
In Structures Affected by this Mutation:	17 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kat2a Mutation:	40 strains or lines available

Original:	J:65002 Xu W, et al., Loss of gcn5l2 leads to increased apoptosis and mesodermal defects during mouse development. Nat Genet. 2000 Oct;26(2):229-32
All:	8 reference(s)