About   Help   FAQ
Dmrt1tm1Zark
Targeted Allele Detail
Summary
Symbol: Dmrt1tm1Zark
Name: doublesex and mab-3 related transcription factor 1; targeted mutation 1, David Zarkower
MGI ID: MGI:2385911
Synonyms: Dmrt1flox, Dmrt1neo
Gene: Dmrt1  Location: Chr19:25483070-25581692 bp, + strand  Genetic Position: Chr19, 20.45 cM, cytoband C2-C3
Alliance: Dmrt1tm1Zark page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:65541
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsThe entire exon 1 was floxed by insertion of a loxP site upstream of the promoter and insertion of a PGK-neo-loxP cassette at intron 1 via homologous recombination. (J:65541)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 6 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dmrt1 Mutation:  48 strains or lines available
References
Original:  J:65541 Raymond CS, et al., Dmrt1, a gene related to worm and fly sexual regulators, is required for mammalian testis differentiation. Genes Dev. 2000 Oct 15;14(20):2587-95
All:  11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/16/2024
MGI 6.23
The Jackson Laboratory