Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Vegfatm2.1Nagy
Name:	vascular endothelial growth factor A; targeted mutation 2.1, Andras Nagy
MGI ID:	MGI:2383985
Synonyms:	VEGFhypo, Vegflo
Gene:	Vegfa  Location: Chr17:46327919-46343295 bp, - strand  Genetic Position: Chr17, 22.79 cM
Alliance:	Vegfatm2.1Nagy page

Germline Transmission:	Earliest citation of germline transmission: J:75937
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout, Reporter) Mutation:    Intragenic deletion   Mutation details: The mutant is a derivative of Vegf1tm2Nagy where the floxed PGK-neo cassette in exon 8 has been removed by mating to a cre deletor strain. (J:75937)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	88 assay results
In Structures Affected by this Mutation:	5 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Vegfa Mutation:	37 strains or lines available

Original:	J:75937 Damert A, et al., Insufficient VEGFA activity in yolk sac endoderm compromises haematopoietic and endothelial differentiation. Development. 2002 Apr;129(8):1881-92
All:	12 reference(s)