Lefty1 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:77125 Norris DP, et al., The Foxh1-dependent autoregulatory enhancer controls the level of Nodal signals in the mouse embryo. Development. 2002 Jul;129(14):3455-68
Assay type:	RNA in situ
MGI Accession ID:	MGI:2183497
Gene symbol:	Lefty1
Gene name:	left right determination factor 1

Probe:	Lefty probe
Probe preparation:	Antisense labelled with digoxigenin RNA
Visualized with:	Alkaline phosphatase

Results

2I (top) ©

Specimen 2I (top): embryonic day 6.5 (more

)

Structure	Level	Pattern	Image	Note
TS9: extraembryonic visceral endoderm	Present	Regionally restricted	2I (top)	Expression is anterior.

2I (bottom) ©

Specimen 2I (bottom): embryonic day 6.5; Nodal^tm1.1Rob/Nodal^tm2Rob (more

)

Structure	Level	Pattern	Image	Note
TS9: extraembryonic visceral endoderm	Absent		2I (bottom)

6A ©

Specimen 6A: embryonic day 8.5 (more

)

Structure	Level	Pattern	Image	Note
TS13: neural tube floor plate	Present	Regionally restricted	6A	Expression is on the left side.

6B ©

Specimen 6B: embryonic day 8.5; Nodal^tm2Rob/Nodal^tm2Rob (more

)

Structure	Level	Pattern	Image	Note
TS13: neural tube floor plate	Absent		6B
TS13: primitive streak	Present	Single cells	6B	Expression is in a few cells near the node.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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